In the recently released IFTF report entitled, Booting Up Mobile Health: From Medical Mainframe to Distributed Intelligence, we forecast that there will be high levels of experimentation and innovation in mobile health devices and services emerging from the Global South.  We expect poorer nations, including much of Sub-Saharan Africa, to develop into the main proving ground for decentralized, mobile models of health care delivery.  This is not only due to the rapid diffusion of mobile technology, but also because 20th-century models of centralized, institutionally managed health care